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MDGL Madrigal Pharmaceuticals, Inc.

NasdaqResearch view

Madrigal Pharmaceuticals, Inc. operates in the Pharmaceutical Preparations industry.

$449.74−2.19%

Oct 16 close · 1D EOD · Databento

HealthcarePharmaceutical PreparationsLarge-capSEC EDGAR FY 2025-12-31

On the WireNo stories on MDGL yet. Follow the company and the next one lands in Following.

What happened

Daily closes · dots are Wire stories

What’s next

Expected around late October, going by its own filing history. The company has not announced a date yet. Its matching report came Nov 4, 2025 and Oct 31, 2024, before the open.

Last report

Jul 30, 2026−9.83%

before the open

Last 4, next close

median 8.83% either way

up 2 of 4

Every report since 2023 →Earnings calendar →

DateEventSourceNext close

Jul 30Earnings release, before the open · 8-KSEC EDGARSEC EDGAR ↗−9.83%

Next close = the first close after the event against the close before it. Prior-session closes only; not a call, not advice.

What happened · big days

23 big days in a year, and what we hold on each

A big day is a close more than 4.07% from the one before, three times MDGL’s median day (1.36%). On 0 of the 23, its peer group moved the same way at least half as far. We show what we hold. We never name a cause.

every other trading daya big day, numbered in the list below±4.07%Hover a bar for its day. Click a big day to open it.

Shaded: since our stories began, Jun 10. Tap a bar for its day.

#DayMDGLWhat we hold that dayGroup (median of 4) · each

1 Nov 4, 2025+7.83%
Resultsgroup +1.4%, did not move with it
1Nov 4, 2025+7.83%
ResultsFirst close after the Nov 4 results filing
+1.4% did not move with itABBV +1.9 · MRK +1.7 · LLY +1.1 · JNJ +0.3
2 Nov 5, 2025+7.02%
Before our storiesgroup +0.5%, did not move with it
2Nov 5, 2025+7.02%
Before our stories
+0.5% did not move with itLLY +2.1 · MRK +0.6 · ABBV +0.4 · JNJ −0.5
3 Nov 11, 2025+9.20%
Before our storiesgroup +2.9%, did not move with it
3Nov 11, 2025+9.20%
Before our stories
+2.9% did not move with itMRK +4.8 · ABBV +3.0 · JNJ +2.9 · LLY +2.3
4 Nov 17, 2025+4.57%
Before our storiesgroup +0.3%, did not move with it
4Nov 17, 2025+4.57%
Before our stories
+0.3% did not move with itJNJ +1.9 · ABBV +0.7 · MRK −0.1 · LLY −0.3
5 Nov 24, 2025+7.29%
Before our storiesgroup +1.0%, did not move with it
5Nov 24, 2025+7.29%
Before our stories
+1.0% did not move with itMRK +2.7 · JNJ +1.1 · LLY +1.0 · ABBV −2.9
6 Dec 19, 2025+8.56%
Before our storiesgroup +0.9%, did not move with it
6Dec 19, 2025+8.56%
Before our stories
+0.9% did not move with itABBV +1.8 · LLY +1.4 · MRK +0.4 · JNJ −0.9
7 Jan 6, 2026−5.16%
Before our storiesgroup +1.5%, did not move with it
7Jan 6, 2026−5.16%
Before our stories
+1.5% did not move with itJNJ +0.2 · MRK +1.3 · ABBV +1.7 · LLY +2.2
8 Jan 9, 2026−7.58%
Before our storiesgroup −1.2%, did not move with it
8Jan 9, 2026−7.58%
Before our stories
−1.2% did not move with itLLY −2.0 · ABBV −1.8 · JNJ −0.7 · MRK −0.4
9 Feb 17, 2026+4.87%
Before our storiesgroup +0.0%, did not move with it
9Feb 17, 2026+4.87%
Before our stories
+0.0% did not move with itABBV +0.6 · MRK +0.1 · JNJ −0.1 · LLY −0.4
10 Feb 19, 2026−11.11%
Resultsgroup +0.2%, did not move with it
10Feb 19, 2026−11.11%
ResultsFirst close after the Feb 19 results filing
+0.2% did not move with itABBV −1.9 · MRK +0.2 · LLY +0.3 · JNJ +0.8
11 Mar 26, 2026+12.30%
Before our storiesgroup −0.3%, did not move with it
11Mar 26, 2026+12.30%
Before our stories
−0.3% did not move with itABBV +1.9 · JNJ −0.3 · MRK −0.4 · LLY −2.1
12 Apr 7, 2026−4.12%
Before our storiesgroup −0.6%, did not move with it
12Apr 7, 2026−4.12%
Before our stories
−0.6% did not move with itMRK −1.3 · JNJ −1.1 · ABBV −0.1 · LLY +0.4
13 May 6, 2026+7.42%
Resultsgroup −0.3%, did not move with it
13May 6, 2026+7.42%
ResultsFirst close after the May 6 results filing
−0.3% did not move with itMRK +0.4 · LLY −0.2 · JNJ −0.4 · ABBV −0.5
14 May 8, 2026−4.64%
Before our storiesgroup −0.7%, did not move with it
14May 8, 2026−4.64%
Before our stories
−0.7% did not move with itLLY −2.7 · MRK −0.8 · ABBV −0.6 · JNJ −0.5
15 Jun 2, 2026−5.90%
Before our storiesgroup +0.1%, did not move with it
15Jun 2, 2026−5.90%
Before our stories
+0.1% did not move with itLLY −1.7 · JNJ −0.3 · MRK +0.4 · ABBV +1.2
16 Jun 3, 2026+7.79%
Before our storiesgroup +0.5%, did not move with it
16Jun 3, 2026+7.79%
Before our stories
+0.5% did not move with itLLY +1.4 · ABBV +0.8 · JNJ +0.2 · MRK −0.8
17 Jul 1, 2026−4.20%
Nothing on MDGLgroup −0.4%, did not move with it
17Jul 1, 2026−4.20%
Nothing on MDGLNo MDGL story, brief or results filing in our record that day
−0.4% did not move with itMRK −2.4 · LLY −0.6 · ABBV −0.2 · JNJ 0.0
18 Jul 10, 2026−4.16%
Nothing on MDGLgroup −1.0%, did not move with it
18Jul 10, 2026−4.16%
Nothing on MDGLNo MDGL story, brief or results filing in our record that day
−1.0% did not move with itLLY −2.3 · MRK −1.2 · JNJ −0.8 · ABBV −0.7
19 Jul 30, 2026−9.83%
Resultsgroup −3.0%, did not move with it
19Jul 30, 2026−9.83%
ResultsFirst close after the Jul 30 results filing
−3.0% did not move with itLLY −4.5 · JNJ −3.7 · ABBV −2.2 · MRK −0.4
20 Jul 31, 2026−5.23%
Nothing on MDGLgroup −0.2%, did not move with it
20Jul 31, 2026−5.23%
Nothing on MDGLNo MDGL story, brief or results filing in our record that day
−0.2% did not move with itABBV −2.5 · LLY −0.5 · JNJ +0.2 · MRK +0.3
21 Aug 4, 2026+5.30%
Nothing on MDGLgroup −0.2%, did not move with it
21Aug 4, 2026+5.30%
Nothing on MDGLNo MDGL story, brief or results filing in our record that day
−0.2% did not move with itJNJ +0.2 · MRK +0.2 · LLY −0.5 · ABBV −0.5
22 Aug 13, 2026−5.38%
Nothing on MDGLgroup +0.7%, did not move with it
22Aug 13, 2026−5.38%
Nothing on MDGLNo MDGL story, brief or results filing in our record that day
+0.7% did not move with itLLY −0.9 · JNJ +0.5 · ABBV +0.8 · MRK +2.0
23 Aug 26, 2026+5.22%
Nothing on MDGLgroup −1.6%, did not move with it
23Aug 26, 2026+5.22%
Nothing on MDGLNo MDGL story, brief or results filing in our record that day
−1.6% did not move with itABBV −1.1 · JNJ −1.1 · MRK −2.1 · LLY −3.6

A story on the same day is not a cause, and a group move is not proof either. Group: the median of LLY, JNJ, ABBV and MRK that day, the largest companies in MDGL’s SEC industry; “moved with MDGL” means the same direction and at least half the size.

What’s next · results

Before the next report: what the first day after the last four did

Six trading days after each results filing (SEC 8-K, Item 2.02). MDGL reports before the open, so day 1 is that day’s close. Each time, day 6 ended on the same side as day 1.

Reported Nov 4, 2025

day 1+7.83%day 6+31.32%

Reported Feb 19, 2026

day 1−11.11%day 6−9.29%

Reported May 6, 2026

day 1+7.42%day 6+3.26%

Reported Jul 30, 2026

day 1−9.83%day 6−6.68%

Next report: expected late October to early NovemberEstimated from the dates of its last four results filings. Not announced. Since the Jul 30 report: −17.76%. Four reports is a small sample.

Every report since 2023 →

Each line is MDGL’s close against its close before the filing, on licensed end-of-day closes. What happened after each report, not a forecast; a move on the day is not a cause.

The numbers · FY2025, filed

SEC EDGAR

Market cap$10.4B

Revenue$958.4M+432.10%

Net income$-288.3M

EPS, diluted$-10.15+41.40%

Operating margin-31.3%

Return on equity-47.8%

Debt / equity0.56

All filed figures

Snapshot

SEC EDGAR · FY 2025-12-31

SectorHealthcare

Market Cap$10.4B

Enterprise Value$10.5B

Income$-288.3M

Sales$958.4M

Book/sh$26.09

Cash/sh$8.82

Dividend TTM—

Payout—

Employees—

IPO—

Quick Ratio3.77

Current Ratio4.01

Debt/Eq0.56

EPS (ttm)$-10.15

EPS this Y41.4%

EPS past 3/5Y—

Sales past 3/5Y—

EPS Y/Y TTM41.4%

Sales Y/Y TTM432.1%

Shs Outstand23.10M

ROA-22.9%

ROE-47.8%

ROIC-40.6%

Gross Margin—

Oper. Margin-31.3%

Profit Margin-30.1%

Every figure here is filed with the SEC. Valuation and estimate metrics (P/E, PEG, EV/EBITDA, price targets, forward EPS) are omitted until our market-data feed is licensed for display — we’d rather show fewer numbers than blank ones. Deeper lines (cash flow, balance sheet) below.

Revenue by fiscal year

FY21

FY22

FY23

$180.1M

FY24

$958.4M

FY25

Operating leverage — margins

GrossOperatingNet

Financials, annual · income and cash flowSEC EDGAR · open ▸

Financials — annual

SEC EDGAR · last 5 FY · tap a row to explain it

USD	FY2021	FY2022	FY2023	FY2024	FY2025
Revenue	$0	$0	$0	$180.1M	$958.4M
Gross Profit	—	—	—	—	—
Operating Income	$-242.5M	$-293.6M	$-380.5M	$-497.9M	$-300.1M
Net Income	$-241.8M	$-295.3M	$-373.6M	$-465.9M	$-288.3M
Diluted EPS	$-14.63	$-17.23	$-17.33	$-17.31	$-10.15
Operating Cash Flow	$-183.9M	$-224.9M	$-324.2M	$-455.6M	$-189.6M
Free Cash Flow	$-184.1M	$-225.1M	$-325.7M	$-457.0M	$-190.0M

Same industry

MDGL against four drug peers, a year at 100

MDGL is up 2.5% in a year. Merck is up 72.1%, Eli Lilly 56.6%, Johnson & Johnson 32.3% and AbbVie 24.3%. All four did more. Weekly closes, Oct 17, 2025 = 100, on a log scale, so the same percentage move is the same height on every line.

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MDGL +2.5%. Merck +72.1%, Eli Lilly +56.6%, Johnson & Johnson +32.3%, AbbVie +24.3%. Weekly closes, Oct 17, 2025 = 100, log scale.

Share this chart

End-of-day closes (Databento EOD), the last close of each week. The four peers are the largest US-listed companies by market value in MDGL’s SEC industry (Pharmaceutical Preparations) with a year of closes. It shows what the closes did; a move here is not a cause, a forecast or a call.

Same industry

In the screener →

LLY$1.18T JNJ$615.9B ABBV$504.4B MRK$360.1B ABT$181.5B PFE$168.6B VRTX$126.7B BMY$122.1B

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Fundamentals sourced from SEC EDGAR filings (public domain). For informational purposes only. Not investment advice.