MRNA Wire Story Reactions & EOD Technical StudyDaily closes (Databento EOD) pinned with every AlgoThesis Wire story (dot colour = next trading day close) and SEC filing
Nov 5, 2026CLOSE $241.461D −6.55%3M +303.71%SMA20 $223.39SMA50 $189.62RSI(14) 60.4
Data provided by Databento (end of day). Next close = the first close after a story against the close before it; official daily closes only, not a call, not advice.
After a story on MRNA, the first close moved a median −3.35%. Up 0 of 3; over the next three trading days, a median +7.03%.
The numbers
fiscal 2025, as filed with the SEC · 66-metric EOD snapshot via Databento
Market cap$103.2B
Enterprise value$101.1B
Revenue$1.9B −39.9%
True FCF (ex-SBC)$-2.5B +49.1%
Rule of 40-146.1%
ROIC-47.2%
True FCF Yield-2.5%
EPS, diluted$-7.26 +21.8%
Modern Valuation (EOD)
Market Cap$103.2B
Enterprise Value$101.1B
EV / True FCF—
EV / FCF—
EV / Gross Profit—
EV / EBIT—
EV / Sales52.03
P / E (GAAP)—
P / FCF—
P / Oper. CF—
P / Book11.93
Owner & Cash Yields
True FCF Yield-2.5%
FCF Yield-2.0%
Owner Earn. Yield-3.2%
Earnings Yield-2.7%
Shareholder Yield−0.5%
Buyback Yield0.0%
Dividend Yield—
Dividend / sh—
Payout Ratio—
FCF / sh$-5.17
EPS (diluted)$-7.26
Compounder & Returns
Rule of 40-146.1%
ROIC-47.2%
Cash ROIC (CROIC)-31.1%
GP / Assets—
ROE-32.6%
ROA-22.9%
Gross Margin—
Oper. Margin-158.1%
Net Margin-145.2%
FCF Margin-106.2%
True FCF Margin-131.1%
Quality & Dilution
Cash Conversion—
Accrual Ratio−7.7%
SBC % of FCF—
SBC % of Rev24.8%
Reinvest. Rate—
Sales Growth Y/Y−39.9%
Sales 3Y CAGR−53.4%
EPS Growth Y/Y+21.8%
FCF Growth Y/Y+49.1%
FCF 3Y CAGR—
Share Change Y/Y+1.3%
Balance Sheet & Scale
Revenue (FY)$1.9B
Gross Profit (FY)—
Oper. Income (FY)$-3.1B
GAAP Net Income$-2.8B
True FCF (ex-SBC)$-2.5B
Cash & Equiv$2.6B
Total Debt$590.0M
Net Cash (Debt)$2.0B
Net Cash % MCap+1.9%
Debt / FCF (yrs)—
Current Ratio3.29399.24M sh
Price & Technicals (EOD)
Perf Week+8.39%
Perf Month+22.89%
Perf Quarter+308.08%
Perf Half Y+397.45%
Perf YTD+342.32%
SMA 20 Dist+8.09%$223.39
SMA 50 Dist+27.34%$189.62
SMA 100 Dist+83.52%$131.57
Window High−6.55%$258.38
Window Low+432.20%$45.37
RSI (14) · Vol60.4114%v
Income Distribution & Cash Flow ConversionHow every dollar of MRNA revenue flows through cost of goods, operating expenses, taxes, GAAP net income, and dilution-adjusted free cash flow
Standard Free Cash Flow (FCF)$-2.1B(-106.2% margin)
Less: Stock-Based Comp (SBC)−$483.0M
True FCF (Owner Cash ex-SBC)$-2.5B(-131.1% of rev)
Revenue by fiscal year
$18.5BFY21
$19.3BFY22
$6.8BFY23
$3.2BFY24
$1.9BFY25
Operating leverage — margins
GrossOperatingNet
Unlocked SEC EDGAR Accounting Statements (USD)All 3 statements · Common-size (% of Revenue / Assets) · YoY growth · Tap any core row to explain
Line Item (USD)
FY2021
FY2022
FY2023
FY2024
FY2025
YoY Δ
4Y CAGR
Trend
Income Statement
Revenue ▸
$18.5B
$19.3B
$6.8B
$3.2B
$1.9B
−39.9%
−43.0%
Cost of Revenue (COGS)
$2.6B
$5.4B
$4.7B
$1.5B
$868.0M
−40.7%
−24.1%
Research & Development (R&D)
$2.0B
$3.3B
$4.8B
$4.5B
$3.1B
−31.1%
+12.0%
Operating Income (EBIT) ▸
$13.3B
$9.4B
$-4.2B
$-3.9B
$-3.1B
+22.1%
—
Income Tax Expense
$1.1B
$1.2B
$772.0M
$-46.0M
$54.0M
+217.4%
−52.7%
GAAP Net Income ▸
$12.2B
$8.4B
$-4.7B
$-3.6B
$-2.8B
+20.8%
—
Diluted EPS ▸
$28.29
$20.12
$-12.33
$-9.28
$-7.26
+21.8%
—
Diluted Shares
431.0M
416.0M
382.0M
384.0M
389.0M
+1.3%
−2.5%
Balance Sheet
Cash & Equivalents
$6.9B
$3.2B
$2.9B
$1.9B
$2.6B
+34.6%
−21.6%
Inventory
$1.4B
$949.0M
$202.0M
$117.0M
$153.0M
+30.8%
−42.9%
Total Current Assets
$16.1B
$13.4B
$10.3B
$8.1B
$6.5B
−19.2%
−20.1%
Total Assets
$24.7B
$25.9B
$18.4B
$14.1B
$12.3B
−12.8%
−15.9%
Total Current Liabilities
$9.1B
$4.9B
$3.0B
$2.2B
$2.0B
−9.9%
−31.7%
Total Debt (Short + Long Term)
$591.0M
$591.0M
$591.0M
$0
$590.0M
—
−0.0%
Total Liabilities
$10.5B
$6.7B
$4.6B
$3.2B
$3.7B
+13.8%
−23.1%
Stockholders' Equity
$14.1B
$19.1B
$13.9B
$10.9B
$8.7B
−20.6%
−11.6%
Net Cash / (Net Debt)
$6.3B
$2.6B
$2.3B
$1.9B
$2.0B
+4.0%
−24.8%
Invested Capital
$7.9B
$16.5B
$11.5B
$9.0B
$6.6B
−26.0%
−4.2%
Cash Flow & Capital Allocation
Operating Cash Flow (OCF) ▸
$13.6B
$5.0B
$-3.1B
$-3.0B
$-1.9B
+37.6%
—
Depreciation & Amortization (D&A)
$232.0M
$348.0M
$617.0M
$185.0M
$211.0M
+14.1%
−2.3%
Stock-Based Compensation (SBC)
$142.0M
$226.0M
$305.0M
$429.0M
$483.0M
+12.6%
+35.8%
Capital Expenditures (CapEx)
$284.0M
$400.0M
$707.0M
$1.1B
$192.0M
−81.7%
−9.3%
Free Cash Flow (FCF) ▸
$13.3B
$4.6B
$-3.8B
$-4.1B
$-2.1B
+49.1%
—
True FCF (ex-SBC Owner Cash)
$13.2B
$4.4B
$-4.1B
$-4.5B
$-2.5B
+43.2%
—
Share Repurchases (Buybacks)
$857.0M
$3.3B
$1.2B
$0
$2.0M
—
−78.0%
Fundamentals, income distribution and multi-year statements from SEC EDGAR filings (public domain). Valuation multiples, performance and technicals computed from Databento 1D EOD closes. For information only, not investment advice.
The Wire at 7 AM ET, free. Top stories with a bull and a bear case on each, every morning. No account needed.
What happened · big days
22 big days in a year, and what we hold on each
A big day is a close more than 8.06% from the one before, three times MRNA’s median day (2.69%). On 0 of the 22, its peer group moved the same way at least half as far. We show what we hold. We never name a cause.
every other trading daya big day, numbered in the list below±8.06%Hover a bar for its day. Click a big day to open it.
Shaded: since our stories began, Jun 10. Tap a bar for its day.
#DayMRNAWhat we hold that dayGroup (median of 4) · each
1 Dec 5, 2025+8.67%
Before our storiesgroup −0.8%, did not move with it
1Dec 5, 2025+8.67%
Before our stories
−0.8% did not move with itEXEL −0.0 · BIIB −0.4 · GILD −1.1 · AMGN −3.0
2 Dec 19, 2025+9.21%
Before our storiesgroup +2.6%, did not move with it
2Dec 19, 2025+9.21%
Before our stories
+2.6% did not move with itEXEL +4.1 · BIIB +2.9 · GILD +2.3 · AMGN +0.9
3 Jan 6, 2026+10.85%
Before our storiesgroup +3.0%, did not move with it
3Jan 6, 2026+10.85%
Before our stories
+3.0% did not move with itBIIB +4.6 · EXEL +3.0 · AMGN +3.0 · GILD +2.6
4 Jan 13, 2026+17.02%
Before our storiesgroup −0.5%, did not move with it
4Jan 13, 2026+17.02%
Before our stories
−0.5% did not move with itEXEL +0.1 · AMGN −0.4 · GILD −0.7 · BIIB −4.0
5 Jan 21, 2026+15.84%
Before our storiesgroup +3.9%, did not move with it
5Jan 21, 2026+15.84%
Before our stories
+3.9% did not move with itBIIB +4.4 · GILD +4.0 · AMGN +3.8 · EXEL +2.4
6 Mar 4, 2026+15.99%
Before our storiesgroup +1.5%, did not move with it
6Mar 4, 2026+15.99%
Before our stories
+1.5% did not move with itBIIB +3.2 · EXEL +2.3 · AMGN +0.6 · GILD +0.3
7 May 8, 2026+11.97%
Before our storiesgroup +0.9%, did not move with it
7May 8, 2026+11.97%
Before our stories
+0.9% did not move with itEXEL +4.2 · BIIB +1.1 · AMGN +0.8 · GILD −2.0
8 Jun 17, 2026+11.55%
Nothing on MRNAgroup −0.4%, did not move with it
8Jun 17, 2026+11.55%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
−0.4% did not move with itBIIB +1.6 · EXEL +0.7 · GILD −1.4 · AMGN −1.8
9 Jun 26, 2026+12.59%
Nothing on MRNAgroup +3.1%, did not move with it
9Jun 26, 2026+12.59%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+3.1% did not move with itBIIB +7.0 · GILD +3.3 · EXEL +2.9 · AMGN +1.6
10 Jul 2, 2026+10.01%
Nothing on MRNAgroup +3.5%, did not move with it
10Jul 2, 2026+10.01%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+3.5% did not move with itGILD +4.2 · AMGN +3.5 · EXEL +3.5 · BIIB +3.0
11 Jul 10, 2026−10.83%
Nothing on MRNAgroup −0.6%, did not move with it
11Jul 10, 2026−10.83%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
−0.6% did not move with itGILD −3.7 · EXEL −1.1 · AMGN −0.1 · BIIB +0.1
12 Aug 7, 2026+9.86%
Nothing on MRNAgroup +1.7%, did not move with it
12Aug 7, 2026+9.86%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+1.7% did not move with itEXEL +3.6 · GILD +1.8 · AMGN +1.5 · BIIB +0.8
13 Aug 19, 2026+176.97%
Nothing on MRNAgroup +3.5%, did not move with it
13Aug 19, 2026+176.97%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+3.5% did not move with itBIIB +4.2 · AMGN +4.0 · GILD +2.9 · EXEL +2.4
14 Aug 20, 2026−23.55%
Nothing on MRNAgroup −2.4%, did not move with it
14Aug 20, 2026−23.55%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
−2.4% did not move with itBIIB −3.3 · GILD −2.8 · AMGN −1.9 · EXEL −1.3
15 Aug 21, 2026+8.86%
Nothing on MRNAgroup +1.2%, did not move with it
15Aug 21, 2026+8.86%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+1.2% did not move with itGILD +1.9 · AMGN +1.3 · BIIB +1.1 · EXEL +0.7
16 Aug 25, 2026+14.36%
Nothing on MRNAgroup +1.3%, did not move with it
16Aug 25, 2026+14.36%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+1.3% did not move with itEXEL +4.0 · GILD +1.4 · BIIB +1.2 · AMGN −0.4
17 Sep 1, 2026+9.93%
Nothing on MRNAgroup +2.2%, did not move with it
17Sep 1, 2026+9.93%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+2.2% did not move with itEXEL +4.1 · GILD +2.5 · AMGN +1.9 · BIIB −0.3
18 Sep 17, 2026+8.55%
Nothing on MRNAgroup +1.8%, did not move with it
18Sep 17, 2026+8.55%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+1.8% did not move with itEXEL +3.0 · GILD +2.2 · BIIB +1.4 · AMGN +0.9
19 Sep 21, 2026+12.27%
Nothing on MRNAgroup +1.0%, did not move with it
19Sep 21, 2026+12.27%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+1.0% did not move with itAMGN +1.9 · BIIB +1.7 · GILD +0.3 · EXEL −1.9
20 Oct 9, 2026+14.21%
Nothing on MRNAgroup +2.3%, did not move with it
20Oct 9, 2026+14.21%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+2.3% did not move with itBIIB +3.3 · GILD +2.8 · AMGN +1.8 · EXEL +1.4
21 Oct 22, 2026−17.57%
Nothing on MRNAgroup +2.2%, did not move with it
21Oct 22, 2026−17.57%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+2.2% did not move with itEXEL +1.1 · AMGN +2.0 · GILD +2.4 · BIIB +5.3
22 Nov 4, 2026+13.11%
Nothing on MRNAgroup +3.0%, did not move with it
22Nov 4, 2026+13.11%
Nothing on MRNANo MRNA story, brief or results filing in our record that day
+3.0% did not move with itGILD +4.2 · AMGN +3.7 · BIIB +2.2 · EXEL +0.6
A story on the same day is not a cause, and a group move is not proof either. Group: the median of AMGN, GILD, BIIB and EXEL that day, the largest companies in MRNA’s SEC industry; “moved with MRNA” means the same direction and at least half the size.
What’s next · results
Before the next report: what the first day after the last four did
Six trading days after each results filing (SEC 8-K, Item 2.02). MRNA reports before the open, so day 1 is that day’s close. 2 of 4 times, day 6 ended on the same side as day 1.
Reported Nov 6, 2025
day 1+3.27%day 6+5.94%
Reported Feb 13, 2026
day 1+5.29%day 6+25.38%
Reported May 1, 2026
day 1−1.24%day 6+18.31%
Reported Jul 31, 2026
day 1−5.35%day 6+2.16%
Next report: expected early-to-mid FebruaryEstimated from the dates of its last four results filings. Not announced. Four reports is a small sample.
Each line is MRNA’s close against its close before the filing, on licensed end-of-day closes. What happened after each report, not a forecast; a move on the day is not a cause.
Same industry
MRNA against four biotech peers, a year at 100
MRNA is up 10.5 times in a year. All four did less: Exelixis (+78.3%), Biogen (+63.6%), Amgen (+49.4%) and Gilead Sciences (+46.8%). Weekly closes, Nov 7, 2025 = 100, on a log scale so a 10.5-fold rise and a 46.8% rise both read honestly.
End-of-day closes (Databento EOD), the last close of each week. The four peers are the largest US-listed companies by market value in MRNA’s SEC industry (Biological Products, (No Diagnostic Substances)) with a year of closes. It shows what the closes did; a move here is not a cause, a forecast or a call.